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BioMS

Biomolecular Mass Spectrometry
and proteomics

Marino Lab

Fabio Marino

Assistant Professor

Our group focuses on antigen discovery and immunobiology, aiming to deepen our understanding of HLA class I and II antigen processing and presentation using mass spectrometry–based proteomics and immunopeptidomics. By studying these processes in both immune and diseased cells, we seek to improve clinical applications, identify targetable HLA-bound antigens, and uncover how T cells recognize antigens. We also develop and apply advanced analytical workflows, including automation, liquid chromatography, ion mobility, mass spectrometry, alternative fragmentation techniques, and bioinformatics. Our lab is part of the Biomolecular Mass Spectrometry and Proteomics group within the Utrecht Institute for Pharmaceutical Sciences (UIPS), Oncode Accelerator (OA), and the Princess Máxima Center (PMC).

Awarded Grants

There are currently no awards noted down.

Group News

  • Postdoc Position in Clinical Antigen Discovery – Marino Lab

    July 21, 2026

    As a clinical Postdoctoral Researcher in the group of dr FabMarino, you will play a central role in advancing the group’s research through the development and application of state-of-the-art immunopeptidomics/proteomics workflows for antigen identification, quantification, and validation. Your work will directly contribute to translational and precision medicine initiatives, with a particular focus on the discovery of […]

    Read more →
  • Postdoc Position in Computational Antigen Discovery

    July 14, 2026

    Within the BioMS group, we have built a specialized team focusing on the discovery of previously unidentified antigens for immunotherapies through mass spectrometry (MS)-based proteomics and immunopeptidomics. We now seek a highly motivated and experienced Postdoctoral Researcher to join our multidisciplinary research team.  Click here to read more!

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Group Members

Amy Kessler

General Member

Ashwin Kallor

General Member

Nefise Çelebi

General Member

Rishov Mukhopadhyay

General Member

2025

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Amy L. Kessler, Kyle L. Fort, Hanno Christoph Resemann, Peter Krüger, Cong Wang, Heiner Koch, Jan-Peter Hauschild, Fabio Marino, Albert J. R. Heck
Molecular & Cellular Proteomics
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Thierry Schmidlin, Enas M. Behiry, Hannah L. Thomas, Garry M. Dolton, Fabio Marino, Samiul Hasan, Magdaléna von Essen, Rose Muthoni Gathungu, Barbara A. Steigenberger, Hayden J. Selvadurai, Joseph D. Dukes, Paul E. Brennan, Owen Brad Spiller, Jonathan D. Silk, Andrew Kelvin Sewell, Nicola Ternette
Cell Reports Methods
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Michal Mateusz Waleron, Ashwin Adrian Kallor, Aleksander Pałkowski, Emilia Daghir‐Wojtkowiak, Piyush Borole, Mikołaj Kocikowski, Karol Połom, Fabio Marino, Beatriz Monterde, Michele Mastromattei, Davide Venditti, Mark D. Stares, Ashita Singh, Theodore Hupp, Christophe Battail, Alexander Laird, Cátia Pesquita, Luis Zapata, Stefan Nicholas Symeonides, Ajitha Rajan, Fabio Massimo Zanzotto, Javier A. Alfaro
bioRxiv (Cold Spring Harbor Laboratory)Preprint

2020

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Fabio Marino, Aikaterini Semilietof, Justine Michaux, HuiSong Pak, George Coukos, Markus Müller, Michal Bassani‐Sternberg
Frontiers in Immunology
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Michele Graciotti, Fabio Marino, HuiSong Pak, Petra Baumgaertner, Anne‐Christine Thierry, Johanna Chiffelle, Marta A. S. Perez, Vincent Zoete, Alexandre Harari, Michal Bassani‐Sternberg, Lana Elias Kandalaft
Vaccines
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Fabio Marino, Aikaterini Semilietof, Michaux Justine, Pak Hui-Song, Coukos George, Mueller Markus, Michal Bassani‐Sternberg
Frontiers in Immunology (Web)

2018

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Sietske Kooijman, Jolanda Brummelman, Cécile A. C. M. van Els, Fabio Marino, Albert J. R. Heck, Elly van Riet, Bernard Metz, Gideon F. A. Kersten, Jeroen L. A. Pennings, Hugo D. Meiring
PLoS ONE
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Jennie Rebecca Lill, Peter A. van Veelen, Stefan Tenzer, Arie Admon, Étienne Caron, Joshua Eric Elias, Albert J. R. Heck, Miguel Marcilla, Fabio Marino, Markus Müller, Bjoern Peters, Anthony Wayne Purcell, Alessandro Sette, Theo Sturm, Nicola Ternette, Juan Antonio Vizcaíno, Michal Bassani‐Sternberg
PROTEOMICS
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Sietske Kooijman, Jolanda Brummelman, Cécile A. C. M. van Els, Fabio Marino, Albert J. R. Heck, Geert P. M. Mommen, Bernard Metz, Gideon F. A. Kersten, Jeroen L. A. Pennings, Hugo D. Meiring
Journal of Proteomics

2017

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Chloé Chong, Fabio Marino, HuiSong Pak, Julien Racle, Roy Thomas Daniel, Markus Müller, David Gfeller, George Coukos, Michal Bassani‐Sternberg
Molecular & Cellular Proteomics
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Wenguang Shao, Patrick G. A. Pedrioli, Witold Wolski, Cristian Scurtescu, Emanuel Schmid, Juan Antonio Vizcaíno, Mathieu Courcelles, Heiko Schuster, Daniel Johannes Kowalewski, Fabio Marino, Cecilia S. Lindestam Arlehamn, Kerrie C. Vaughan, Bjoern Peters, Alessandro Sette, Tom H. M. Ottenhoff, Krista E. van Meijgaarden, Natalie Eva Nieuwenhuizen, Stefan H. E. Kaufmann, Ralph Schlapbach, John C. Castle, Alexey I. Nesvizhskii, Morten Nielsen, Eric W. Deutsch, David S Campbell, Robert L. Moritz, Roman A. Zubarev, Anders Jimmy Ytterberg, Anthony Wayne Purcell, Miguel Marcilla, Alberto Paradela, Qi Wang, Catherine E. Costello, Nicola Ternette, Peter A. van Veelen, Cécile A. C. M. van Els, Albert J. R. Heck, Gustavo A. de Souza, Ludvig Magne Sollid, Arie Admon, Stefan Stevanović, Hans‐Georg Rammensee, Pierre Thibault, Claude Perreault, Michal Bassani‐Sternberg, Ruedi Aebersold, Étienne Caron
Nucleic Acids Research
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Alba Cristobal, Fabio Marino, Harm Post, Henk van den Toorn, Shabaz Mohammed, Albert J. R. Heck
Analytical Chemistry
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Belén Montoya Jiménez, María Luisa Palmero Colado, Vanessa Pérez, Fabio Marino, C. Monje Salvador
Argos: Informativo Veterinario

2016

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Adán Alpízar, Fabio Marino, António Ramos-Fernández, Manuel Lombardía, Anita Jekő, Florencio Pazos, Alberto Paradela, César A. Santiago, Albert J. R. Heck, Miguel Marcilla
Molecular & Cellular Proteomics

View Fabio Marino on ORCID →