Excellent Research and Education with a Focus on Mass Spectrometry
The Biomolecular Mass Spectrometry and Proteomics group develops and implements innovative mass spectrometric methods for the more efficient and detailed characterization of peptides and proteins in relation to their biological function. A large emphasis is on the structural characterization of proteins and their post-translational modifications as well as the investigation of protein complexes and protein interactions. In short, the group applies biomolecular mass spectrometry to problems in proteomics, cell biology, biotherapeutics, immunology and in structural biology.
BioMS in Numbers
Female Scientists
Male Scientists
Utrecht University Departments
Mass Spectrometers
Nationalities
PhD students
Post Doctoral Researchers
Borrels a Year
Offices
Papers Published in 2025
Master and Bachelor Students
Liquid Chromatograpy Systems
We are Embedded In Utrecht Science Park
The Biomolecular Mass Spectrometry & Proteomics has its laboratories and offices in the Kruyt-building on the Utrecht Life Science campus. We really feel here at an ideal position as a spider in a web. We are centrally located in between many of our key users and collaborators rom the different departments and faculties, and also ULS research institutes such as the Hubrecht Institute and RIVM and hospitals (UMC, PMC and WKZ), and companies such as Merus, Genmab, Gyes, QVQ and Abvion.
The Utrecht research group is nationally and internationally embedded in large-scale proteomics infrastructures, with the Netherlands Proteomics Centre (NPC) as a central coordinating hub. Established in 2003, the NPC has played a leading role in shaping the Dutch proteomics roadmap and has coordinated all national proteomics initiatives since its foundation. Proteomics became part of the Netherlands Genomics Initiative in 2003 and was included in the first Dutch Roadmap for Large-Scale Research Infrastructures in 2012. The first major roadmap-funded project, Proteins At Work (2013–2018), was coordinated by the NPC and funded by the Dutch Research Council (NWO) with €13.5 million. This was followed by X-Omics (2018–2028), a €40 million initiative integrating genomics, proteomics, metabolomics, and data stewardship. In 2025, the NPC also became part of the newly awarded BioBeyond_NL roadmap project, which will establish national infrastructure for advanced glycoprotein and antibody analysis. Internationally, the NPC has coordinated major European infrastructure projects, including PRIME-XS (2011–2015) and EPIC-XS (2019–2024), providing transnational access to advanced proteomics technologies. Currently, the NPC participates in EASI-OMICS, which supports European researchers through access to cutting-edge multi-omics platforms. Additionally, the NPC is linked to Instruct-ERIC, providing mass spectrometry services via the Dutch Instruct Centre
